A recent study has shown great potential for chokeberry juice in the prevention of cardiovascular disease (CVD). The research was conducted by researchers at the University of Nottingham in the UK. The research appears to be the first scientific investigation of the ability of chokeberry juice to reduce blood pressure, improve blood lipid profile, and lower total cholesterol level. The study was published in the prestigious Journal of American Heart Association. The research was led by Professor Shyam Sundaram, senior research fellow at the University of Nottingham and Head of cardiovascular research at the University of Nottingham Healthcare NHS Trust.
The current research is a novel approach to counter the potential risk factors for the development of atherosclerosis, particularly in the elderly. It used a mouse model of healthy aging humans monitored for a series of serum lipidographic, glucose, and blood pressure, associated with risk factors and their subsequent response to supplementing with antioxidant-rich chokeberry extract. The results showed that a high dose of the polyphenol compound significantly decreased blood pressure, improved total cholesterol level, and prevented the development of the metabolic syndrome, which is characterized by the accumulation of fat, especially in the neck, abdomen, and liver. The metabolic syndrome is a cluster of unfavorable conditions, brought about by the autonomic nervous system, that are known to contribute to the development of heart failure. The symptoms of the metabolic syndrome include hypertension, hyperlipidemia, high blood pressure, low density lipoprotein (HDL) cholesterol levels, and abnormal metabolic rates. The researchers had previously shown that the polyphenol compound Quercetin from green tea exerts anti-inflammatory and anti-oxidant effects in laboratory mice, which are likely to have effects similar to those of Quercetin in human patients.
Currently, there are a variety of different brands of supplement available on the market. As with any dietary supplement, the best choice is to research and select the one that has the most health benefits and a good track record of success. Most nutritional supplements will list clinical trials and supportive scientific data, along with supporting information such as dosage calculations, side effects, contraindications, etc. If you choose a brand that does not have such information, or fails to mention the number of clinical trials and scientific studies that it has undergone and been through, you should avoid using the product, since there are higher chances that the product might not be effective.